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Structure and Function  Research Products Contact
BReMeL, an innovative Hellenic Biotechnology Company (under-establishment) will be based in Thessaloniki, and in full operation will include three Departments: Commercial - Scientific - Educational. We envisage that the achievement of the Company's goals concerning the production of Biopharmaceuticals and Products of Regenerative Medicine has in the long term the potential of changing the "landscape" in the field of the Greek Pharmaceutical Industry and Medical Biotechnology Research. In the past, BReMeL's existing investment project for the production of three raw biopharmaceutical  materials in purified form (recombinant insulin, recombinant HBsAg, penicillin) had been selected for funding by the European Program NSRF 2007-2013 with the maximum allowable amount of € 290.000,00, characterized as "extremely dynamic" and its innovation was graded with excellent (20/20).  a) Development of a new therapeutic strategy for the safer and more efficient administration of anti-CD19 CAR T-cells to refractory B-acute lymphoblastic leukemia. b) Generation of a specialized cell line from human Langerhans beta-cells for insulin production.c) Formation of experimental cellular models - disease modeling - by inducing the differentiation of mesenchymal stem cells (MSCs) or induced pluripotent cells (iPSCs), in order to study the pathophysiological mechanisms of incurable diseases such as neurodegenerative diseases, heart diseases, etc. and test new drugs. The Greek Pharmaceutical Industry does not produce any active pharmaceutical ingredients (APIs) at all and only formulates the imported ones. Therefore, the survival of the corresponding domestic drug production depends exclusively on APIs imports from international markets, mostly India and China.   The primary target for BReMeL is to become the first domestic company for production on a massive scale of:
(a) APIs in a purified form for the production of biopharmaceuticals according to the specifications of the corresponding monographs of the European Pharmacopoeia VIII (Ph.Eur VIII), making use of the "cellular factory" of micro-organisms and the recombinant DNA technology. (b) Regenerative medicine products by applying innovative methods of Cellular and Molecular Biology. 
For more information on BReMeL, you can contact via the contact form, by e-mail or phone.

Welcome to BReMeL!!

We welcome you to the BReMeL's website, a new under-establishment Greek company for the development of biotechnology products for use in medical practice and research.


1stvideo: The most important points of the currently followed strategy to fight R/R B-ALL with anti-CD19 CAR T-cells (this video will be soon uploaded).

2nd video: An innovative approach for therapy of R/R B-ALL with anti-CD19 CAR T-cells, aiming at preventing the occurrence of the serious side effects (it will be uploaded after the 1st one, when a patent priority date for the method will be declared).

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